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酚肤哌睛酮（反应停，thalidomide）已显示对治疗HIV－1阳性病例的特发性口腔和咽部口疮性溃疡有效。酞胺哌啶酮对肿瘤坏死因子（TNF-a）的抑制可能是其作用的重要机制。考虑到TNF-a对克隆病有一定影响，且抗TNF-a抗体可减轻克隆病的活动性。本文作者用酞胺呢院酮治疗1例因克隆
Phenalbumin (thalidomide) has been shown to be effective in treating idiopathic oral and pharyngeal aphthous ulcers in HIV-1-positive cases. Inhibition of tumor necrosis factor (TNF-a) by thalidomide may be an important mechanism of its action. Taking into account the TNF-a has a certain impact on the Crohn’s disease, and anti-TNF-a antibody can reduce the activity of Crohn’s disease. The author of this paper with thalidomide treatment of 1 case due to cloning