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目的观察左旋卡尼汀改善陈旧性心肌梗死患者心肌供血的疗效。方法选择并纳入滨海新区汉沽街社区卫生服务中心2 0 1 3年3月-2 0 1 5年9月陈旧性心肌梗死患者6 8例,进行分组研究,每组3 4例。治疗组行常规治疗+左旋卡尼汀,对照组行常规治疗。对比两组患者临床治疗效果,胸痛、乏力、胸闷、心悸和气促5项症状缓解率的差异。结果治疗组治疗总有效率明显高于对照组,胸痛、乏力、胸闷3项症状缓解率明显高于对照组,差异均有统计学意义(P<0.0 5)。两组患者心悸和气促2项症状缓解率的差异无统计学意义(P>0.0 5)。结论左旋卡尼汀改善陈旧性心肌梗死患者心肌供血的疗效确切,可有效改善患者心肌供血功能,缓解临床症状,值得在临床中推广和应用。
Objective To observe the efficacy of L-carnitine in improving myocardial blood supply in patients with old myocardial infarction. METHODS: A total of 68 elderly patients with myocardial infarction were selected and included in Hangu Street Community Health Center, Binhai New Area from March 2003 to September 2005. The treatment group received routine treatment + L-carnitine, control group routine treatment. The differences of clinical symptoms, chest pain, fatigue, chest tightness, palpitations and shortness of breath in the five groups were compared. Results The total effective rate of the treatment group was significantly higher than that of the control group. The relief rate of the three symptoms of chest pain, fatigue and chest tightness were significantly higher than those of the control group (P <0.05). Two groups of patients palpitation and shortness of breath two symptom relief rate difference was not statistically significant (P> 0.0 5). Conclusion L-carnitine is effective in improving myocardial blood supply in patients with obsolete myocardial infarction. It can effectively improve the function of myocardial blood supply and relieve clinical symptoms, which is worthy of promotion and application in clinical practice.