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自应用骨髓移植或采用抗胸腺细胞球蛋白(ATG)及大剂量甲基强的松龙(MP)以来,严重型再生障碍性贫血的预后明显改善。本文作者观察了4例严重再障病人(男女各2,22-49岁,1例属特发性,3例属药物所致)。ATG静脉点滴8天,15mg/kg,MP静脉连续点滴4天,20mg/kg,又10mg/kg4天,尔后每4天减半量。维持剂量0.5mg/kg/日,口服。例1、2、4,分别口服7个月、5个月、43天以上。此外加用Oxymetholone 1.5mg/kg/日,口服。例1、4分
The prognosis for severe Aplastic Anemia has improved significantly since bone marrow transplantation or with anti-thymocyte globulin (ATG) and high-dose methylprednisolone (MP). The authors observed four patients with severe aplastic anemia (men and women, 2,22-49 years of age, one case of idiopathic, three cases due to drugs). ATG intravenous drip 8 days, 15mg / kg, MP intravenous drip for 4 days, 20mg / kg, and 10mg / kg 4 days, then every 4 days halved. Maintenance dose 0.5mg / kg / day, orally. Cases 1,2,4, were orally 7 months, 5 months, 43 days or more. In addition, add Oxymetholone 1.5mg / kg / day orally. Example 1,4 points