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新生儿呼吸窘迫综合征(以下简称RDS)是新生儿期发病率、病死率较高的疾病之一。病理学上称为新生儿肺透明膜病。本文回顾分析79例新生儿RDS肺病理改变,探讨其发病机理。临床及病理资料分析一、临床资料二、临床诊断临床诊断主要为:特发性RDS(38例),表现为出生后6小时内(个别在出生后6—12小时内)出现进行性呼吸困难;其余为宫内窘迫,产时窒息或羊水吸入等(41例),也表现为出生后进行性呼吸困难。患儿曾分别给予持续正压吸氧(CPAP),呼气未正压吁吸(PEEP)和间歇正压呼吸(IPP 病例资料均来源于1980年1月至1985年12月间本院收治后死亡的新生儿RDS患者,共79例,占同期死亡尸解的446例新生儿的17.7％,其中男44例,女35例(1.25:1)。其简况见表1。
Neonatal respiratory distress syndrome (hereinafter referred to as RDS) is one of the neonatal morbidity, high mortality. Pathologically known as neonatal hyaline membrane disease. This paper retrospectively analyzed 79 cases of neonatal RDS lung pathological changes to explore its pathogenesis. Clinical and pathological data analysis 1. Clinical data 2. Clinical diagnosis The main clinical diagnosis is idiopathic RDS (38 cases), presenting with progressive dyspnea within 6 hours after birth (individual within 6-12 hours after birth) ; The rest were intrauterine distress, asphyxia during labor or inhalation of amniotic fluid (41 cases), also showed progressive dyspnea after birth. Children were given continuous positive pressure oxygen (CPAP), expiratory pressure is not positive pressure (PEEP) and intermittent positive pressure breathing (IPP cases were from January 1980 to December 1985 after hospital treatment A total of 79 newborns died of RDS, accounting for 17.7% of 446 neonates who died during the same period of death, including 44 males and 35 females (1.25: 1).