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Objective:This study aimed to describe the implementation of the surgical safety check policy and the surgical safety checklist for invasive procedures outside the operating room (OR) and evaluate its effectiveness.Methods:In 2017,to improve the safety of patients who underwent invasive procedures outside of the OR,the hospital quality and safety committee established the surgery safety check committee respon-sible for developing a new working plan,revise the surgery safety check policy,surgery safety check form,and provide training to the related staff,evaluated their competency,and implemented the updated surgical safety check policy and checklist.The study compared the data of pre-implementation(Apr to Sep 2017) and two post-implementation phases (Apr to Sep 2018,Apr to Sep 2019).It also evaluated the number of completed surgery safety checklist,correct signature,and correct timing of signature.Results:The results showed an increase in the completion rate of the safety checklist after the program implementation from 41.7％ (521/1,249) to 90.4％ (3,572/3,950),the correct rates of signature from 41.9％(218/521) to 99.0％ (4,423/4,465),and the correct timing rates of signature from 34.4％ (179/521) to 98.5％(4,401/4,465),with statistical significance (P ＜ 0.01).Conclusion:Implementing the updated surgery safety check significantly is a necessary and effective measure to ensure patient safety for those who underwent invasive procedures outside the OR.Imple-menting surgical safety checks roused up the clinical staff's compliance in performing safety checks,and enhanced team collaboration and communication.