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目的:对河南产毛叶香茶菜化学成分进行研究。方法:运用各种色谱技术和波谱分析对其化学成分进行分离鉴定。结果:分离鉴定了20个二萜化合物。结论:化合物1-3为三个新的对映-贝壳杉烷二萜类化合物,结构分别为7β-15β,16β三羟基-6β,17β二乙酰氧基-7α,20-环氧-对映-贝壳杉烷(1)、16(S)-6β,11α,17p三羟基一6,20一环氧一la,7β内酯-6,7-断裂-对映-贝壳杉-15酮(2)和6α,11α二羟基-1α乙酰氧基-7,20-内酯-6,7-断裂-对映-贝壳杉-16-烯-15-酮(3),依次命名为毛叶香茶莱丙素、丁素和戊素;化合物4和5为一对新化合物,其结构为3α,15α,1β6,17β,18β五羟基-对映-松香-7(8)-烯的丙酮化物,其丙酮化缩合部分互为对映体,分别命名为毛叶香茶菜庚素(4)和辛素(5)。
Objective: To study the chemical constituents of Agrocybe aegypti in Henan Province. Methods: The chemical components were separated and identified by various chromatographic techniques and spectral analysis. Results: 20 diterpene compounds were isolated and identified. CONCLUSION: Compounds 1-3 are three new enantio-kaurene diterpenoids with the structures of 7β-15β, 16β-trihydroxy-6β, 17β-diacetoxy-7α, 20-epoxy-enantiomer. - Kauransane (1), 16(S)-6β, 11α, 17p tris-hydroxy-6,20-epoxy-la, 7β-lactone-6,7-fracture-enantio-kaurin-15-one (2 ) and 6α,11α-dihydroxy-1α-acetoxy-7,20-lactone-6,7-cleavage-enantio-kauthen-16-ene-15-one (3), named in turn as the leafy tea Leptin, buprelin and pentylene; Compounds 4 and 5 are a pair of new compounds with the structure of 3α, 15α, 1β6, 17β, 18β pentahydroxy-enanti-rosin-7(8)-ene acetonide, The acetonide condensation moieties are enantiomers of each other and are named as C. acuminata (4) and Cintin (5), respectively.