Influence of gene modified (IL-7, IL-4 and B7) tumor cell vaccines on tumor antigen presentation

• 作 者: Sophie Cayeux Günther Ric
• 机 构: Robert-RssleKlinik,VirchowKlinikum,MedicalFacultyoftheHumboldtUniversityofBerlin,LindenbergerWeg80,1
• 出 处: 中国实验血液学杂志
• 发表日期: 1997年3期
• 关键词: PRESENTATION vaccines FASHION asked ADJUVANT indirectly suppression immunized RE

We have previously shown that tumor cellsgenetically modified to co-express IL-4 or IL-7 and B7. 1have increased immunogenicity and provided vaccinessuperior to single gene transfectants or tumor cells/adjuvant mixture. Tumor antigens can be presented eit