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目的 探讨儿童狼疮性肾炎（ＬＮ）的临床及实验室检查特征。方法 分析７３ 例ＬＮ 患儿的临床表现，统计其发生率、实验室检查结果阳性率，并与１３０ 例成人ＬＮ进行比较。结果 儿童ＬＮ 男女比例为１∶１１；以无症状性血尿和（ 或） 蛋白尿为多发表现；与成人相比肾病综合征并发肾功能损害发生率高。结论 儿童ＬＮ 仍以女性为多见；无症状性蛋白尿和（ 或） 血尿为其常见表现；以肾病综合征为表现时易出现肾功能损害。
Objective To investigate the clinical and laboratory features of children with lupus nephritis (LN). Methods The clinical manifestations of 73 cases of LN were analyzed. The incidence of LN and the positive rate of laboratory test were compared with 130 cases of adult LN. Results The ratio of LN to children in children was 1:11. Asymptomatic hematuria and / or proteinuria were the most frequent manifestations. Compared with adults, the incidence of nephrotic syndrome complicated with renal dysfunction was high. Conclusions LN is still more common in women than in children; asymptomatic proteinuria and / or hematuria are common manifestations; nephrotic syndrome is the most common manifestation of renal dysfunction.