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目的 探讨急性病毒性心肌炎患儿血清心脏肌钙蛋白T(CTnT)的临床意义。方法 40 例急性病毒性心肌炎患儿进行酶免法测定血清CTnT,同时测定心肌酶谱CK、CK-MB、LDH等,2w k 后复检。结果 40 例急性病毒性心肌炎患儿血清CTnT浓度治疗前较治疗后明显升高,与正常对照组比较有显著差异(P< 0.01)。与心肌酶谱对照,血清CTnT较CK-MB的增高率明显,持续时间长。结论 急性病毒性心肌炎患儿血清CTnT明显升高,提示心肌受累,其特异性高于CK-MB。持续增高可提示预后不良,应结合EKG变化,进一步加强心肌保护性治疗措施。
Objective To investigate the clinical significance of serum cardiac troponin T (CTnT) in children with acute viral myocarditis. Methods 40 cases of children with acute viral myocarditis enzyme immunoassay for the determination of serum CTnT, myocardial enzyme CK, CK-MB, LDH, etc., after 2wk retest. Results Serum CTnT concentrations in 40 children with acute viral myocarditis were significantly higher than those before treatment, which were significantly different from the normal control group (P <0.01). Compared with myocardial enzymes, serum CTnT than CK-MB increased significantly, for a long time. Conclusions The serum CTnT in children with acute viral myocarditis is significantly higher than that in CK-MB. Continued to increase may prompt a poor prognosis, should be combined with EKG changes, to further strengthen the myocardial protective treatment.