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目的:了解医院肺炎克雷伯菌感染的分布与耐药情况。方法:采用VITEK-32微生物鉴定仪鉴定,纸片琼脂扩散法药敏试验进行统计分析。结果:200株肺炎克雷伯菌中痰液、尿液、血液和分泌物标本占88%,其中痰液70.9%、尿液9.8%、血液5.8%、分泌物1.5%。其耐药率最低的是亚胺培南/西司他丁(0),其次为阿米卡星(25%)、头孢哌酮/舒巴坦钠(35%)、头孢美唑(37.5%),其余均大于40.0%。结论:医院内肺炎克雷伯菌耐药现象突出,临床应重视其流行情况并合理使用抗菌药物。
Objective: To understand the distribution and drug resistance of Klebsiella pneumoniae in hospital. Methods: VITEK-32 microbial identification instrument identification, paper agar diffusion susceptibility testing for statistical analysis. Results: The specimens of sputum, urine, blood and secretions from 200 strains of Klebsiella pneumoniae accounted for 88%, of which 70.9% were sputum, 9.8% were urine, 5.8% were blood and 1.5% were secretions. The lowest rate of resistance was imipenem / cilastatin (0), followed by amikacin (25%), cefoperazone / sulbactam (35%), cefmetazole (37.5% ), The rest are more than 40.0%. Conclusion: The Klebsiella pneumoniae resistance in the hospital is prominent. The clinic should pay attention to the prevalence and use the antibacterials rationally.