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氯霉素治疗伤寒已有20余年历史。1968年自甲氧苄胺嘧啶(TMP)与磺胺甲基异恶唑(SMZ)合用治疗伤寒倡用以来,疗效满意。我院自1973年应用国产TMP(北京制药厂)-SMZ和复方新诺明片(东北第六制药厂,每片含TMP80毫克,SMZ400毫克),治疗伤寒共133例,并与同期病人113例用氯霉素治疗作对比观查,综合分析于后。一、材料来源:将我院1973-1974年住院确诊之伤寒246例分三组:“TMP-SMZ”(下简称增效Ⅰ组)100例、复方新诺明片(下简称增效Ⅱ组)33例和氯霉素组113例。增效Ⅰ组和氯霉素组按入院顺序无选择性使
Chloramphenicol treatment of typhoid fever has more than 20 years of history. In 1968 since the trimethoprim (TMP) and sulfamethoxazole (SMZ) in combination with the treatment of typhoid fever, the effect is satisfactory. Our hospital since 1973, the application of domestic TMP (Beijing Pharmaceutical Factory) -SMZ and cotrimoxamine tablets (Northeast Pharmaceutical Factory, each containing TMP80mg, SMZ400mg), the treatment of typhoid fever a total of 133 cases, and with the same period the patient 113 cases Chloramphenicol treatment for comparison, comprehensive analysis in the later. First, the source of the material: In our hospital from 1973 to 1974 confirmed 246 cases of typhoid fever divided into three groups: “TMP-SMZ” (hereinafter referred to as efficiency group Ⅰ) 100 cases, ) 33 cases and chloramphenicol group 113 cases. Synergistic group Ⅰ and chloramphenicol group by admission order of non-selective