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[目的]观察肾康3号治疗慢性肾衰竭(CRF)的临床疗效。[方法]按中华内科杂志标准及全国中医肾衰研讨会标准,选择CRF患者共40例,随机分治疗组20例,对照组20例。治疗组用肾康3号治疗,对照组用单味大黄治疗,观察治疗前后尿素氮、肌酐、肌酐清除率、白蛋白、血红蛋白等指标及临床症状的变化。[结果]治疗组临床疗效优于对照组(P<0.05)。[结论](1)肾康3号治疗慢性肾衰竭的临床疗效优于单味大黄;(2)肾康3号通过补益脾肾、降浊祛瘀的作用,对慢性肾衰竭辨证属脾肾气虚证为主者,起到显著改善症状,改善肾功能并延缓慢性肾衰竭进展。
[Objective] To observe the clinical effect of Shenkang 3 in treating chronic renal failure (CRF). [Methods] According to the standard of Chinese Internal Medicine and the National Seminar on TCM Renal Failure, 40 patients with CRF were randomly divided into treatment group (n = 20) and control group (n = 20). The treatment group was treated with Shenkang 3 and the control group with single rhubarb treatment. The changes of urea nitrogen, creatinine, creatinine clearance rate, albumin, hemoglobin and other clinical symptoms before and after treatment were observed. [Results] The clinical efficacy of the treatment group was better than that of the control group (P <0.05). [Conclusion] (1) The clinical efficacy of Shenkang 3 in treating chronic renal failure is better than that of single rhubarb. (2) Shenkang No.3 can treat spleen and kidney of chronic renal failure by tonifying the spleen and kidney, reducing blood stasis and removing blood stasis. Qi deficiency-based, play a significant improvement in symptoms, improve renal function and delay the progress of chronic renal failure.