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目的分析19例老年梅毒的临床特征及实验室检测结果。方法根据梅毒诊断标准,对病人进行血清TRUST滴度检测及TPPA试验确诊。确诊后用头孢三嗪1g肌肉注射,1次/d,连用15d,同时观察病人治疗前、治疗3、6、9个月和1年后的TRUST滴度变化情况。结果 19例患者男17例,女2例;年龄65~93岁,均已婚,10例丧偶或离异。治疗后1年,TRUST滴度转阴16例(84.2%),3例滴度降至1∶2~1∶4。结论梅毒治疗前后血清滴度的变化可用来判定疗效,头孢三嗪治疗老年梅毒疗效确切。应加强对老年群体的健康教育,进行必要的性知识及性病防治知识宣传,以减少或杜绝梅毒的发生和传播。
Objective To analyze the clinical characteristics and laboratory test results of 19 elderly syphilis. Methods According to the diagnostic criteria of syphilis, TRUST titer of serum and TPPA test were confirmed. After diagnosis, 1 g of ceftriaxone was intramuscularly injected once a day for 15 days. At the same time, the change of TRUST titer before, 3, 6, 9 months and 1 year after treatment was observed. Results 19 patients were 17 males and 2 females, aged 65-93 years, both married and 10 widowed or divorced. One year after treatment, the TRUST titer was negative in 16 cases (84.2%) and the titer in 3 cases was reduced to 1: 2 ~ 1: 4. Conclusion The change of serum titer before and after syphilis treatment can be used to determine the curative effect. Ceftriaxime treatment of elderly syphilis is effective. Health education for the elderly should be strengthened and necessary knowledge of sexual and STD prevention should be disseminated so as to reduce or eliminate the occurrence and spread of syphilis.