超重与肥胖儿童血脂状况分析

• 作 者: 韦厚明 李斌 冯翔
• 机 构: 深圳市龙岗区公共卫生应急办公室,龙岗区疾病预防控制中心,中山大学公共卫生学院,
• 出 处: 现代预防医学
• 发表日期: 2009年16期
• 关键词: 肥胖儿童 超重 载脂蛋白 血脂异常 血脂 对比研究 单纯性肥胖儿童 三酰甘油 正常体重 脂蛋白

[目的]了解超重、肥胖儿童血脂水平,为儿童肥胖的干预提供依据。[方法]对深圳市龙岗区168名肥胖儿童、160名超重儿童和175名正常体重儿童分别进行血脂水平测定。采集空腹肘静脉血测定血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白AI(Apo AI)载脂蛋白B(Apo B)、脂蛋白(a)[Lp(a)]。[结果]肥胖儿童TC、TG、LDL-C、Apo B、Lp(a)水平高于体重正常组儿童,而HDL-C、Apo AI水平则低于体重正常组儿童,差异有统计学意义(P值均﹤0.05)。HDL-C,Apo AI水平为肥胖组﹤超重组﹤对照组,TC,TG,LDL-C,Apo B,Lp(a)水平为肥胖组﹥超重组﹥对照组。TG,HDL-C,LDL-C3项指标异常率肥胖组较对照组高(P值均﹤0.05)。[结论]单纯性肥胖儿童在学龄期即可出现脂类代谢异常,应及早采取干预措施。 [Objective] To understand the level of blood lipid in overweight and obese children and provide basis for the intervention of childhood obesity. [Method] The blood lipid levels of 168 obese children, 160 overweight children and 175 normal weight children in Longgang District of Shenzhen City were determined respectively. The fasting cubital vein blood was collected for determination of serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein AI Apolipoprotein B (Apo B), Lipoprotein (a) [Lp (a)]. [Results] The levels of TC, TG, LDL-C, Apo B and Lp (a) in obese children were higher than those in normal weight children, while the levels of HDL-C and Apo AI in obese children were lower than those in normal weight children P <0.05). The levels of HDL-C and Apo AI in the obese group were as follows:> overweight group