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目的探讨坦索罗辛在输尿管下段结石体外震波碎石(ESWL)后辅助排石中的效果。方法 148例输尿管下段结石患者随机分成对照组和治疗组,对照组ESWL后应用山莨菪碱10mg,3次/d,金钱草颗粒10g,3次/d;治疗组ESWL后予以口服坦索罗辛0.4mg,1次/d,金钱草颗粒10g,3次/d。观察结石排出情况、是否再次发生肾绞痛而需要镇痛药治疗和药物的副反应。每例者观察时间为2周。结果对照组排石率为32.9%,治疗组排石率为64.0%,无明显副反应发生。结论坦索罗辛能提高输尿管下段结石ESWL后的排石率,减少再发生肾绞痛的机率,且安全有效,可作为输尿管下段结石ESWL后的辅助排石方法。
Objective To investigate the effect of tamsulosin in the auxiliary row of stones after external ureteral shock wave lithotripsy (ESWL). Methods 148 cases of lower ureteral calculi patients were randomly divided into control group and treatment group, the control group after ESWL application of anisodamine 10mg, 3 times / d, money grass particles 10g, 3 times / d; treatment group after ESWL oral tamsulosin 0.4mg, 1 time / d, money grass particles 10g, 3 times / d. Observation of stone discharge, whether renal colic occurs again and the need for analgesic drug treatment and side effects. Each case was observed for 2 weeks. Results In the control group, the rate of discharged stones was 32.9%, and the rate of discharged stones in the treatment group was 64.0%, with no obvious side-reaction. Conclusion Tamsulosin can improve the rate of stone removal after ESWL in the lower ureteral calculi and reduce the chance of reoccurrence of renal colic and is safe and effective. It can be used as an auxiliary stone discharging method after ESWL of lower ureteral calculi.