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目的研究探讨在糖尿病肾病的诊断中采用血清视黄醇结合蛋白(RBP)与肾功指标[尿素氮(BUN)、尿肌酐(Cr)、胱抑素C(Cys-C)]联合检测的临床价值。方法 78例接受治疗的糖尿病肾病患者作为试验组,另选取78例身体健康者作为对照组,同时对两组的血清RBP与肾功指标(BUN、Cr、Cys-C)联合检测,观察对比两组的检测结果。结果通过对两组的检测结果观察,试验组的RBP检测值(63.28±22.35)mg/L明显高于对照组的检测值(41.59±11.98)mg/L,同时,试验组肾功指标(BUN、Cr、Cys-C)的检测值均明显高于对照组,差异均具有统计学意义(P<0.05)。结论采用血清RBP与肾功指标共同对糖尿病肾病进行诊断,可以提前检测到此类疾病的发生,早期采取措施进行治疗,患者可尽早恢复健康并防止疾病的恶化。
Objective To investigate the clinical application of combination of serum retinol binding protein (RBP) and renal function (BUN, urine creatinine, Cystatin C) in the diagnosis of diabetic nephropathy value. Methods 78 patients with diabetic nephropathy treated as experimental group and 78 healthy controls were selected as control group. Serum RBP and renal function parameters (BUN, Cr and Cys-C) were detected in both groups. Group test results. Results The RBP test (63.28 ± 22.35) mg / L in the test group was significantly higher than that in the control group (41.59 ± 11.98) mg / L by observing the test results of the two groups. Meanwhile, the renal function index , Cr, Cys-C) were significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusions The diagnosis of diabetic nephropathy by using serum RBP and renal function indexes can detect the occurrence of such diseases in advance and take measures for early treatment. Patients can recover their health and prevent the deterioration of the disease as soon as possible.