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目的:观察肾功能障碍感染性休克患者应用持续血液净化的治疗效果。方法:资料选取本院2013年7月-2014年7月收治的肾功能障碍感染性休克患者共90例,随机分为研究组与对照组,研究组45例予血液进化治疗,对照组45例予血液透析治疗,观察治疗前后两组肾功能指标、血气分析指标及升压药物使用浓度。结果:研究组血肌酐(113.26±7.34)μmol/L,尿素氮(5.07±0.62)mmol/L,均显著优于对照组,比较差异明显具统计学意义(P<0.05),研究组PaO2(91.42±8.56)mmHg,HCO3-(23.85±3.21)mmol/L,均显著优于对照组,比较差异明显具统计学意义(P<0.05),研究组升压药使用浓度显著低于对照组,比较差异明显具统计学意义(P<0.05)。结论:肾功能障碍感染性休克患者应用持续血液净化的治疗效果显著。
Objective: To observe the therapeutic effect of continuous blood purification in patients with septic shock with renal dysfunction. Methods: Ninety patients with septic shock of renal dysfunction admitted to our hospital from July 2013 to July 2014 were selected and randomly divided into study group and control group, 45 cases in study group were treated with blood evolution, 45 cases in control group To hemodialysis treatment, observed before and after treatment, renal function parameters, blood gas analysis and step-up drug use concentration. Results: Serum creatinine (113.26 ± 7.34) μmol / L and urea nitrogen (5.07 ± 0.62) mmol / L in the study group were significantly better than those in the control group (P <0.05) 91.42 ± 8.56) mmHg and (23.85 ± 3.21) mmol / L, respectively, which were significantly better than those of the control group (P <0.05). The concentrations of the used booster drugs in the study group were significantly lower than those in the control group The difference was statistically significant (P <0.05). Conclusion: The therapeutic effect of continuous blood purification in patients with renal failure and septic shock is significant.