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背景:脑卒中后情绪障碍以焦虑、抑郁常见,但是有关老年脑梗死患者恢复期情绪障碍的研究报告较少。目的:探讨老年脑梗死患者恢复期情绪障碍的特点以及情绪障碍与神经功能障碍的关系。设计:病例-对照研究。单位:苏州市广济医院精神科和苏州市第二人民医院神经内科。对象:2001-05/2003-06苏州市第二人民医院神经内科住院后出院的患者87例(病例组),男48例,女39例,年龄61～84岁。均首次发病,病程在第3个月的恢复期者。选择本院健康体检人员68例为对照组,神经系统检查和躯体检查正常,无精神病史,无痴呆表现,男39例,女29例,年龄60～82岁。方法:根据统一的指导语,在病程第3个月完成症状自评量表(SCL-90)和改良爱丁堡-斯堪的那维亚量表(SSS)评定,一致性检验Kappa值为0.82。主要观察指标:①SCL-90总分和因子分。②SSS总分。结果:病例组SCL-90总分、阳性项目、阳性总分、阳性均分均高于对照组(t=4.14～8.09,P=0.000)。病例组SCL-90躯体化因子、强迫因子、人际关系因子、抑郁因子、焦虑因子、恐怖因子、精神病性因子评分高于对照组(u=2.107～8.811,P=0.000)。两组在敌对和偏执因子的差异无统计学意义(P>0.05)。病例组SCL-90总分及因子分与神经功能缺损总分呈正相关(r=0.806～0.293,P<0.01)。结论:老年脑梗死患者恢复
Background: Post-stroke mood disorder is common in anxiety and depression, but there are few reports on mood disorders during recovery in elderly patients with cerebral infarction. Objective: To investigate the characteristics of mood disorders in convalescent patients with senile cerebral infarction and the relationship between mood disorders and neurological dysfunction. Design: Case-control study. SETTING: Department of Neurology, Guangji Hospital, Suzhou Second People’s Hospital, Suzhou. PARTICIPANTS: 87 patients (case group), 48 males and 39 females, aged 61-84 years, were discharged from the hospital of Department of Neurology, Second People’s Hospital of Suzhou City from May 2001 to June 2003. The first incidence, the duration of recovery in the first 3 months. 68 healthy controls were chosen as the control group, with normal neurological examination and physical examination, no history of mental illness and no dementia. There were 39 males and 29 females, aged 60-82 years old. Methods: According to the unified guideline, SCL-90 and SS-SSA were completed at the third month of the course of disease. The consistency test showed that the Kappa value was 0.82. MAIN OUTCOME MEASURES: ①SCL-90 total score and factor score. ②SSS total score. Results: The SCL-90 score, positive items, positive total score and positive mean score in case group were all higher than those in control group (t = 4.14-8.08, P = 0.000). SCL-90 somatic factors, coercion factors, interpersonal factors, depression factors, anxiety factors, terror factors and psychotic factors in the case group were significantly higher than those in the control group (u = 2.107-8.811, P = 0.000). There was no significant difference between hostile and paranoid factors in both groups (P> 0.05). There was a positive correlation between SCL-90 score and total score of neurological deficit in case group (r = 0.806-0.293, P <0.01). Conclusion: Elderly patients with cerebral infarction recovered