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由于原发性骨髓增生异常综合征(MDS)在儿童中相对罕见,因此其自然史、演变、发病机制及儿童MDS与成人MDS的关系尚无详细研究。资料与方法按法-美-英(FAB)诊断标准,1979年1月～1991年9月在英国Hacettepe儿童医院1200例急性白血病患儿中共发现33例16岁以下原发性MDS病例。按外周血和骨髓特征,患儿分类为:难
Because of the relatively rare occurrence of primary myelodysplastic syndrome (MDS) in children, its natural history, evolution, pathogenesis, and the relationship between childhood MDS and adult MDS have not been studied in detail. Materials and Methods 33 cases of idiopathic MDS under 16 years of age were found in 1,200 children with acute leukemia at Hacettepe Children’s Hospital in England from January 1979 to September 1991 according to the diagnostic criteria of FAB. According to the characteristics of peripheral blood and bone marrow, children are classified as: Difficult