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本文报告在坦桑尼亚沿海地区进行现场试验的结果。在距达累斯萨拉姆以北30km的Boko村,血检6～17岁学生150名。试验前14天未服过抗疟药。恶性疟原虫(P. f.)阳性者按WHO标准氯喹剂量治疗,观察7天。患者在严密监察下口服总剂量25mg/kg氯喹基质,3天分服的剂量为10、10和5mg/kg。末次服药后当天留取尿液作Wilson-Edeson试验检查以确证氯喹被吸收。缺席超过1天的患者或尿中氯喹阴性者皆不统计在内。在另一个村庄Mabwe-Pande,血检
This article reports the results of a field trial conducted in the Tanzanian coastal area. In Boko village, 30 km north of Dar es Salaam, 150 students aged 6 to 17 were tested. 14 days before the test did not take antimalarial drugs. Plasmodium falciparum (P. f.) -positive patients according to WHO standard dose of chloroquine treatment, observed for 7 days. Patients under oral close orally with a total dose of 25mg / kg chloroquine matrix, 3-day dose of 10,10 and 5mg / kg. Urine was collected on the day after the last dose for Wilson-Edeson test to confirm that chloroquine was absorbed. Patients who were absent for more than one day or those who were out of urine were not counted. In another village Mabwe-Pande, a blood test