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目的：探讨综合护理干预对预防精神病患者便秘的临床效果。方法将80例精神病患者随机分为两组，研究组给予综合护理干预，对照组给予常规护理干预，观察2个月。结果研究组预防精神病患者便秘的显效率为52．7％、总有效率为85．8％，对照组分别为25．1％、42．3％，研究组显效率、总有效率显著高于对照组（χ2＝6．37、15．63，P＜0．01）。结论综合护理干预能有效预防精神病患者发生便秘，有利于提高患者的生活质量。“,”Objective To explore the clinical result of comprehensive nursing in‐terventions in preventing psychotic constipation .Methods Eighty mental patients were randomly assigned to two groups ,research group received comprehensive nursing interventions and control group did routine nursing interventions for 2 months .Results Obvious and total effective rate of preventing psychotic con‐stipation were respectively 52 .7% and 85 .8% in research and 25 .1% and 42 .3% in control group ,the for‐mer was significantly higher than the latter (χ2 = 6 .37 ,15 .63 ,P< 0 .01) .Conclusion Comprehensive nursing interventions could effectively prevent psychotic constipation and is beneficial to the improvement of patients’ quality of life .