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1938年Mann等首次从牛红血球中分离得到了超氧化物歧化酶(Superoxide Dismutase简称SOD),1969年Mccord等进一步发现了它的生物活性。超氧化物歧化酶的主要功能是催化歧化超氧阴离子自由基O_2~-,O_2~-+O_2~-+2H~+→+O_2+H_2O_2,使细胞免受O_2~-的氧化性损伤,因此,它在防御氧的毒
Mann et al. First isolated superoxide dismutase (SOD) from bovine red blood cells in 1938 and further discovered its biological activity in 1969. The main function of superoxide dismutase is to catalyze the disproportionation of superoxide anion radicals O_2 ~ -, O_2 ~ - + O_2 ~ - + 2H ~ + → + O_2 + H_2O_2 so that the cells are protected from the oxidative damage of O_2 ~ It is in the defense of oxygen poisoning