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患者张某,男,63岁.因高血压、冠心病而间断使用辅酶A、ATP肌肉注射,以往使用国产者从无过敏反应.此次于1983年9月27日始用日本进口的ATP肌肉注射每日1支,9月30日10时注完拔针后即觉全身不适,头面部发热感,视物模糊,舌肿大且活动不灵活,咽喉部阻塞感,口周及上肢麻木.查体:患者情绪稍显不安,神清,对答切题但吐词含糊不清;无紫绀,面部及上肢皮肤潮红.双上肢有散在丘疹,直径约2mm左右;眼眶湿润,球结膜充血、水肿,舌明显肿大,舌体左缘有一水泡直径约为10×6mm.呼吸平稳,两肺无干湿啰音,心音有力,心率80次,律齐,血压130/60(平时150~160/90~95mmHg),肢端温暖.
Patients Zhang, male, 63 years old due to high blood pressure, coronary heart disease and intermittent use of coenzyme A, ATP intramuscular injection, the past use of domestic producers from allergic reactions.This September 27, 1983 began with Japan imported ATP muscle Injection daily 1, September 30 at 10 o’clock injection needle after feeling discomfort, head and face fever, blurred vision, swollen tongue and activity is not flexible, throat obstruction, perioral and upper limb numbness. Check the body: the patient feeling a little disturbed, clear, the answer to the question but the vague word vague; no cyanosis, facial and upper limb skin flushing .Above the upper extremity with papules, diameter of about 2mm or so; eyes moist, conjunctival hyperemia, edema, The tongue is obviously swollen, the left edge of the tongue has a blister diameter of about 10 × 6mm. Breathing stable, dry and wet rales of both lungs, heart sound, heart rate 80 times, law Qi, blood pressure 130/60 (usually 150 ~ 160/90 ~ 95mmHg), extremities warm.