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目的:探讨临床上门诊质子泵抑制剂合理用药的实际情况。方法:我们对2014年6月-2016年6月期间我院开具的300份质子泵抑制剂类药物处方的相关资料进行回顾性分析。我们详细观察、记录所有处方的患者基本信息、诊断情况以及用药情况等等,之后进行有效地整理汇总,按照“四查十对”的标准进行分析对比。结果:经过比对与分析,我们发现质子泵抑制剂的使用情况为:消化科使用131份,外科使用46份,其与为其他关联科室;质子泵抑制剂的用药诊断与患者的实际情况相符的处方为214份,欠合理的有65份,完全不相符的有21份;在质子泵抑制剂当中,使用最多的药物是奥美拉唑118份;用药情况不合理的处方有11份,其中无适应症用药7份,与实际诊断情况不符的有4份;质子泵抑制剂同其他药物联合用药是,抗菌药物的使用情况最多,达到了164份;对处方药物的用量进行抽查发现均符合临床用药需求。结论:研究表明,不合理处方及用药情况仍有发生,为了避免错误用药及不良状况的发生,临床医师和药师应加强对质子泵抑制剂适应证、用法用量、联合用药等的观察力度,减少不合理用药情况的发生,提高临床上合理用药的水平。
Objective: To investigate the actual situation of rational use of proton pump inhibitors in clinic. METHODS: We retrospectively analyzed data on 300 prescriptions for proton pump inhibitors issued in our hospital between June 2014 and June 2016. We observed in detail, record the basic information of all patients in the prescription, diagnosis and medication, etc., after the effective summary of the summary, in accordance with “four check ten pairs ” standard comparison analysis. Results: Through the comparison and analysis, we found that the use of proton pump inhibitors: the use of 131 parts of the Department of Gastroenterology, 46 cases of surgical use, which is associated with other departments; proton pump inhibitor medication diagnosis consistent with the actual situation of patients Of the prescriptions for the 214, 65 were not justified, completely inconsistent with 21; among proton pump inhibitors, the most commonly used drugs are omeprazole 118; irrational use of medication in 11 cases, Among them, 7 were not indicted and 4 were inconsistent with the actual diagnosis. The combination of proton pump inhibitor and other drugs was the most widely used antibacterial, reaching 164; the random sampling of prescription drugs In line with clinical drug needs. Conclusion: The study shows that unreasonable prescriptions and medication still occur. In order to avoid wrong medication and adverse reactions, clinicians and pharmacists should strengthen the observation of proton pump inhibitor indications, usage and dosage, combination therapy and so on, and reduce Irrational use of drugs, improve the level of clinical rational use of drugs.