,Substrate-Induced Degradation of the α/β-Fold Hydrolase KARRIKIN INSENSITIVE2 Requires a Functional

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Dear Editor,Derived from but vegetation,karrikins (KAR) are butenolide chemicals that stimulate seed germination and enhance seedling responses to light.Genetic and biochemical studies have identified KARRIKIN INSENSITIVE2 (KAI2) as a putative karrikin receptor protein (reviewed by Waters et al.,2014).KAI2 is an α/β-fold hydrolase and a paralog of DWARF14 (D14;AtD14 in Arabidopsis),and both possess the conserved catalytic triad of Ser,His,and Asp residues typical of this class of hydrolytic enzymes.
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