妊娠期体重指数的变化与小于胎龄儿

• 作 者: Gheng C.J. Bommarito K. NoguchiA. 宁亮
• 机 构: Department of Surger y Div. of Plast. and Reconstr. Surgery Washington Univ. School of Medicine On
• 出 处: 世界核心医学期刊文摘(妇产科学分册)
• 发表日期: 2005年09期
• 关键词: 小于胎龄儿 妊娠期 体重 母体因素 母体 新生儿 子痫 正常出生体重儿 胎龄 密苏里州

OBJECTIVE: To estimate whether maternal weight changes between pregnancies i nf luence the risk for small for gestational age (SGA) births. METHODS: SGA cases ( n = 8,062) below the tenth percentile birth weight for gestational age were sele cted from liveborn singletons born of Missouri residents during 1989-1997. Norm al weight controls (n = 8,062) were selected according to birth year. The risk o f SGA from interpregnancy body mass index (BMI) change and other maternal factor s was estimated using logistic regression analysis. RESULTS: An increase in BMI between pregnancies decreased SGA risk (adjusted odds ratio = 0.8; 95%confidenc e interval 0.7, 1.0). Other risk factors were prior SGA (4.4; 4.0, 4.8), preecla mpsia/eclampsia (2.6; 2.1, 3.2), maternal cardiac disease (1.8; 1.1, 2.9), inade quate weight gain (1.9; 1.8, 2.2), and cigarette smoking (1.9; 1.7, 2.3 for 1-9 cigarettes per day; 2.5; 2.2, 2.8 for 10-19/d; and 2.8; 2.5, 3.3 for 20/d or m ore). CONCLUSION: Increase in interpregnancy BMI lowers SGA risk, but adequate w eight gain during pregnancy is more effective.

OBJECTIVE: To estimate whether maternal weight changes between pregnancies i nf luence the risk for small for gestational age (SGA) births. METHODS: SGA cases (n = 8,062) below the tenth percentile birth weight for gestational age were sele cted from liveborn singletons born of Missouri residents during 1989-1997. Norm al weight controls (n = 8,062) were selected according to birth year. The risk of SGA from interpregnancy body mass index (BMI) change and other maternal factor s was estimated using logistic regression analysis. RESULTS : An increase in BMI between pregnancies decreased SGA risk (adjusted odds ratio = 0.8; 95% confidenc e interval 0.7, 1.0). Other risk factors were prior SGA (4.4; 4.0, 4.8), preecla mpsia / eclampsia 3.2), maternal cardiac disease (1.8; 1.1, 2.9), inadequate weight gain (1.9; 1.8, 2.2), and cigarette smoking (1.9; 1.7, 2.3 for 1-9 cigarettes per day; -19 / d; and 2.8; 2.5, 3.3 for 20 / d or m ore). CONCLUSION: Increase in inter pregnancy BMI lowers SGA risk, but adequate w eight gain during pregnancy is more effective.