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观察了36例难治性肾病患儿应用藻酸双酯钠(PSS)抗凝降脂治疗前后血液流变学,血浆胆固醇和白蛋白的变化以及近期临床效果。结果表明,治疗后血液流变学指标明显降低,血浆胆固醇明显降低,血浆白蛋白明显增高,与肝素对照组比较差异有显著性意义(P<0.05)。临床症状明显改善,总有效率为94%,与肝素对照组比较差异有显著性意义(P<0.05)。提示:PSS可作为难治性肾病抗凝降脂治疗的首选药物之
The changes of hemorheology, plasma cholesterol and albumin before and after anticoagulant lipid-lowering therapy in 36 children with refractory nephropathy were observed and their clinical effects were observed. The results showed that after treatment, the indexes of hemorheology were obviously decreased, the plasma cholesterol was significantly decreased, and the plasma albumin was significantly increased, which was significantly different from that of the heparin control group (P <0.05). Clinical symptoms improved significantly, the total effective rate was 94%, compared with the heparin control group, the difference was significant (P <0.05). Tip: PSS can be used as refractory nephropathy anticoagulant lipid-lowering treatment of choice for the drug