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目的探讨未经手术治疗的食管和/或贲门癌性狭窄支架置入术后1年内再狭窄部位组织的病理形态学特征。方法收集黄石市三家医院6年来食管和/或贲门癌性狭窄支架置入术治疗患者85例,术后1年内再狭窄部位取活检组织进行病理分析。结果 85例未经手术治疗,采取支架置入术,患者术后1年内再狭窄者44例,25例因肿瘤组织过生长(tumor-overgrowing,TG)引起,19例系肉芽组织形成及纤维化(granulation and fibrosis,GF)引起;支架上端再狭窄19例中,TG7例、GF12例:支架下端再狭窄21例中,TG15例、GF6例,上下端均有再狭窄4例。结论食管和/或贲门癌性狭窄支架置入术后1年内再狭窄的发生,部分由TG引起,部分是由GF引起。支架上端再狭窄以GF多见,下端再狭窄以TG多见。
Objective To investigate the histopathological features of the restenosis within 1 year after the surgical treatment of esophageal and / or cardial stenosis stents. Methods Eighty - five patients with esophageal and / or cardia cancer stenosis were enrolled in three hospitals in Huangshi City in the past six years. Pathological analysis was performed on the restenosis site within 1 year after operation. Results 85 cases were treated with stenting without stenting. Forty-four patients were restenosed in one year after operation, 25 were caused by tumor-overgrowing (TG), 19 were granulation tissue formation and fibrosis (GR). Among the 19 cases with upper restenosis, 7 cases were TG7 and 12 cases were GF12. Among the 21 cases with stent restenosis, there were 15 cases of TG and 6 cases of GF. There were 4 cases of restenosis in the upper and lower ends of the stent. Conclusions The incidence of restenosis within 1 year after implantation of esophageal and / or cardiac cancer stenosis stents is partly due to TG and partly due to GF. Stent upper restenosis to GF more common, lower restenosis to TG more common.