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老年非霍奇金淋巴瘤(Non-Hodgkin’s Lymphoma,NHL)患者由于合并其他疾病,治疗剂量通常低于年轻患者。但对于耐受性好的老年NHL,也可考虑标准的化疗方案,CHOP或R-CHOP可能是较好的选择,在化疗的早期使用G-CSF预防可作为一个常规来考虑。其他更强的化疗策略,如多于4药联合化疗、化疗+放疗、高剂量化疗后的自体骨髓移植,则更应该强调个体化策略。
Patients with elderly non-Hodgkin’s Lymphoma (NHL) usually receive lower doses of treatment than younger patients due to other disease combinations. However, for well-tolerated elderly NHLs, standard chemotherapy regimens may also be considered. CHOP or R-CHOP may be the preferred choice. Prevention of G-CSF early in chemotherapy may be considered as a general rule. Other stronger chemotherapeutic strategies, such as autologous bone marrow transplantation after more than 4 combined chemotherapy, chemotherapy plus radiotherapy, and high-dose chemotherapy, should emphasize individualized strategies.