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目的探讨中枢神经系统血管母细胞瘤的临床特点、手术技巧和疗效。方法回顾性分析我院2009年06月至2014年06月17例中枢神经系统血管母细胞瘤显微手术患者的临床数据、影像学特征、手术效果和随访资料。结果主要症状包括头痛、共济失调和肢体功能障碍。17例行MRI检查,6例行CT检查,3例行DSA检查,1例行MRA检查,大囊小结节型10例,均为单发,实质性7例,6例多发。13例显微镜下一期全切,1例显微镜下二期全切,3例显微镜下切除大的病变,小的病变随访。无手术死亡病例。随访3月-5年,神经功能改善15例,无明显变化2例,肿瘤全切者无肿瘤复发,3例未切除的小的病变随访未增大。结论 MRI对中枢神经系统血管母细胞瘤具有重要的诊断价值,显微外科治疗中枢神经系统血管母细胞瘤安全有效,术后并发症少。
Objective To investigate the clinical features, surgical techniques and curative effects of central nervous system hemangioblastoma. Methods The clinical data, imaging features, surgical outcomes and follow-up data of 17 patients with central nervous system hemangioblastoma undergoing microsurgery in our hospital from June 2009 to June 2014 were retrospectively analyzed. Results The main symptoms include headache, ataxia and limb dysfunction. Seventeen patients underwent MRI examination, six patients underwent CT examination, three patients underwent DSA examination, one patient underwent MRA examination, and 10 patients had large cystic nodules. All of them were solitary, substantial and 6 were multiple. 13 cases underwent a total resection under one microscope, one case underwent second stage resection under the microscope, 3 cases underwent microsurgical resection of large lesions and small lesions were followed up. No surgical deaths. Followed up for 3 months to 5 years, 15 cases improved neurological function, no significant change in 2 cases, tumor resection without tumor recurrence, 3 cases of small resection of small lesions did not follow up. Conclusion MRI has important diagnostic value for central nervous system hemangioblastoma. Microsurgical treatment of central nervous system hemangioblastoma is safe and effective, with fewer postoperative complications.