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高血压与心血管疾病密切相关,而脉压是反应血压波动变化的指标,可以更好的反应血管结构和功能的改变。近年来,越来越多的研究证实脉压是心血管疾病的危险因子,其作用独立于其它心血管疾病危险因素。本文从脉压的流行病学研究,病理生理基础及与降压药物疗效的关系等方面对脉压与心血管疾病的联系进行了综述,提出在临床高血压防治过程中,加强对脉压的重视和干预,可以更好的改善患者的预后,减少心血管事件的发生。
Hypertension and cardiovascular disease are closely related, and pulse pressure is an indicator of changes in blood pressure fluctuations, can better reflect changes in vascular structure and function. In recent years, more and more studies have confirmed that pulse pressure is a risk factor for cardiovascular disease and its effect is independent of other cardiovascular disease risk factors. This article reviewed the relationship between pulse pressure and cardiovascular disease in terms of the epidemiological study of pulse pressure, the basis of pathophysiology and the relationship with the effect of antihypertensive drugs. It is suggested that in the course of clinical prevention and treatment of hypertension, Emphasis and intervention, can better improve the prognosis of patients and reduce the incidence of cardiovascular events.