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目的：探讨ＩＣＵ采用双相气道正压（ＢＩＰＡＰ）压力支持通气治疗多种心肺疾病的适应证范围、监测指标的选择和评价治疗作用。方法：对采用ＢＩＰＡＰ压力支持通气的３３例患者进行心率、血氧饱和度（ＳａＯ２）、平均血压（ＭＢＰ）、呼气末二氧化碳分压（ＰｅｔＣＯ２）、呼吸频率和节律及血气分析等指标的监测。结果：慢性阻塞性肺病（ＣＯＰＤ）并呼吸衰竭患者治疗２～４小时后ＰａＯ２和ＳａＯ２明显提高，通气前后比较Ｐ＜０．０５；ＰａＣＯ２和ＰｅｔＣＯ２亦有降低，但无显著性差异；能有效地改善支气管哮喘及阻塞性睡眠呼吸暂停综合征（ＯＳＡＳ）的通气状态；减慢急性肺水肿患者的心率，促进心功能的恢复；对于各种病因的低氧血症，治疗２～４小时后均得以纠正。结论：ＢＩＰＡＰ压力支持通气基本不影响血压，对心率和呼吸频率无负性影响，不增加循环系统负担，无明显并发症。
Objective: To explore the range of indications, the selection of monitoring indexes and the evaluation of therapeutic effect of ICU using biphasic positive airway pressure (BIPAP) pressure support ventilation in treating various cardiopulmonary diseases. Methods: The heart rate, blood oxygen saturation (SaO2), mean blood pressure (MBP), end-tidal carbon dioxide partial pressure (PetCO2), respiratory rate and rhythm and blood gas analysis were monitored in 33 patients with BIPAP pressure- . Results: PaO2 and SaO2 were significantly increased in patients with COPD and respiratory failure two to four hours after treatment, P <0.05 before and after ventilation; PaCO2 and PetCO2 also decreased, but no significant difference; effective Improve the bronchial asthma and obstructive sleep apnea syndrome (OSAS) ventilation state; slow down the heart rate of patients with acute pulmonary edema and promote the recovery of cardiac function; for a variety of causes of hypoxemia, after 2 to 4 hours of treatment Be corrected. Conclusion: BIPAP pressure support ventilation basically does not affect blood pressure, no negative impact on heart rate and respiratory rate, no increase of circulatory system burden, no obvious complications.