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用膜片钳技术的细胞贴附式和内面向外式，在分离培养的新生大鼠小脑皮质颗粒细胞膜上记录到钾离子通道电流，有以下的生理特性，最常见的通道电导为２５ｐＳ，单通道电流幅度、开放时间、开放概率均受膜电位控制，通道开放时间分布直方图可用双指数拟合，无时间依赖性失活，不依赖钙离子，能被ＴＥＡ阻断，表明此通道可能为延迟整流型Ｋ＋通道。提示，小脑皮质颗粒细胞存在有不失活的２５ｐＳ钾离子通道，不同于文献报道的，可能是一种新亚型的钾离子通道。
Using patch-clamp technique for cell attachment and inwards-facing outward, K + channel currents were recorded on isolated and cultured neonatal rat cerebellar cortical granulosa cell membranes with the following physiological properties. The most common channel conductance was 25 pS The channel current amplitude, open time and open probability were all controlled by membrane potential. The histogram of channel open time distribution could be fitted by double exponential function without time-dependent inactivation, which could be blocked by TEA without calcium ion, indicating that this channel may be Delay rectified K + channel. Tip, there is a non-deactivating 25pS potassium channel in cerebellar granule cells, which is different from the reported potassium channel in the new subtype.