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目的:探讨18氟-脱氧葡萄糖(18F-FDG)正电子发射计算机体层摄影(PET-CT)在卵巢癌术后监测中的应用价值。方法:16例卵巢癌患者经肿瘤细胞减灭术和术后化疗或放疗,临床完全缓解6个月以上。行18F-FDG PET-CT检查,结果与手术病理结果对照。结果:18F-FDG PET-CT发现了9例患者,有复发或转移,共发现病灶直径0.3~3.2cm 23处病灶。手术病理证实9例(56%)无假阳性,无假阴性,诊断准确率100%;诊断复发或转移灶的敏感性、特异性、准确率、阳性预测值和阴性预测值分别为78%、78%、78%、90%和58%。PET-CT显示与术中所见病灶的大小、部位均一致。结论:18F-FDGPET-CT在卵巢癌的术后监测中有很高的诊断价值。
Objective: To investigate the value of 18F-FDG positron emission computed tomography (PET-CT) in postoperative monitoring of ovarian cancer. Methods: Twenty-six patients with ovarian cancer were treated with cytoreductive surgery and postoperative chemotherapy or radiotherapy, and their clinical outcomes were completely relieved over 6 months. Line 18F-FDG PET-CT examination, the results and surgical pathology results. Results: Nine patients were found by 18F-FDG PET-CT, with recurrence or metastasis. A total of 23 lesions with diameter of 0.3 ~ 3.2cm were found. Nine cases (56%) showed no false positive, no false negative and 100% diagnostic accuracy. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the diagnosis of recurrence or metastasis were 78% 78%, 78%, 90% and 58%. PET-CT showed the size and location of lesions seen in the surgery were consistent. Conclusion: 18F-FDG PET-CT in the postoperative surveillance of ovarian cancer has a high diagnostic value.