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目的 :分析肾移植后不同的免疫抑制用药方案对移植效果、副作用及长期存活的影响。方法 :根据不同用药组合将 2 0 1例患者分为环孢素A(CsA)、硫唑嘌呤 (Aza)、强的松 (Pred)三联治疗组 ,CsA、霉酚酸酯 (MMF)、Pred三联治疗组 ,CsA和Pred二联治疗组 ,Aza和Pred传统二联治疗组 ,统计分析 4组患者排斥反应和肾存活情况。结果 :三联治疗组 1、3、5年存活率高于传统二联治疗组 ,排斥反应发生率也明显降低。结论 :肾移植后三联治疗组早期急性排斥反应发生率明显低于二联治疗组。
OBJECTIVE: To analyze the effects of different immunosuppressive regimens after kidney transplantation on the effects of transplantation, side effects and long-term survival. Methods: A total of 210 patients were divided into three groups: CsA, Aza, Pred group, CsA, MMF, Pred Triple therapy group, CsA and Pred combined treatment group, Aza and Pred traditional two combined treatment group, statistical analysis of four groups of patients with rejection and renal survival. Results: The survival rates in one, three, and five years in triple therapy group were significantly higher than those in traditional two combined therapy group, and the incidence of rejection was significantly lower. Conclusion: The incidence of early acute rejection in the triple therapy group after renal transplantation was significantly lower than that in the two combined therapy group.