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1984年诺贝尔化学奖授予美国生物化学家罗伯特·梅里菲尔德,以表彰他探索出极为简便的固相肽合成法,对发展新药物和遗传工程所作出的原创性贡献。肽是精准的蛋白质片断,其分子只有纳米般大小。多肽固相合成法是在固体载体上进行化学转化以合成肽类和蛋白质的化学过程。1965年梅里菲尔德设计制成第一台自动化合成仪,先后合成了血管紧张素、催产素和胰岛素等大量蛋白质,尤其是1969年他用这台仪器高速合成由124个氨基酸残基组成的核糖核酸酶A,而
1984 Nobel Prize in Chemistry awarded to US biochemist Robert Meri Field, in recognition of his exploration of extremely simple solid phase peptide synthesis, the development of new drugs and genetic engineering made by the original contribution. Peptides are precise pieces of protein whose molecules are only nano-sized. Peptide solid phase synthesis is the chemical process of chemical transformation on solid supports to synthesize peptides and proteins. 1965, Meri Field designed the first automated synthesizer, has synthesized a large number of proteins such as angiotensin, oxytocin and insulin, especially in 1969 he used this instrument high-speed synthesis of 124 amino acid residues consisting of ribonucleic acid Enzyme A, however