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近年来,在冠心病的药物治疗方面,有了突飞猛进的发展。作者根据近年来文献和本人体会,综述如下: 一、心绞痛的治疗心绞痛是缺血性心脏病(冠心病)最常见的类型。药物治疗首选硝酸盐类药物。重症可静滴硝酸甘油10～30mg溶于250～500ml5％葡萄糖液中,40～100ug/分效果较为明显。Page等用硝酸甘油等静滴治疗67例患者,95.5％治疗期间症状改善,62.7％胸疼消失。钙阻滞剂治疗心绞痛是近年心血管药物治疗中最重要的进展之一。通过阻滞心肌细胞的慢通道,抑制钙离子内流,降低心肌收缩力,扩张冠脉和周围小动脉,降低心脏负荷及心肌耗氧量,对解除冠脉痉
In recent years, in the treatment of coronary heart disease, there has been rapid development. The author based on the literature in recent years and my experience, summarized as follows: First, the treatment of angina pectoris is ischemic heart disease (coronary heart disease) the most common type. Drug treatment preferred nitrate drugs. Severe intravenous nitroglycerin 10 ~ 30mg dissolved in 250 ~ 500ml5% glucose solution, 40 ~ 100ug / min effect is more obvious. Page and other intravenous nitroglycerin treatment of 67 patients, 95.5% during treatment, symptoms improved, 62.7% chest pain disappeared. Calcium blockers for angina pectoris is one of the most important advances in cardiovascular drug therapy in recent years. By blocking the slow passage of myocardial cells, inhibition of influx of calcium, reduce myocardial contractility, dilate the coronary arteries and peripheral arteries, reduce cardiac load and myocardial oxygen consumption, the lifting of coronary artery spasm