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为探讨肝细胞癌各种组织学类型与分化度的关系,对60例肝细胞癌进行常规制备石蜡切片73张和对12例肝细胞癌进行超薄切片。结果表明:①肝细胞癌的组织学多样化,一张切片可有两种或更多种的形态学变化。②肝透明细胞癌的形态比较单一,癌细胞肿大,胞核相对小,细胞分化比较高。③癌细胞呈梭形或小细胞形,胞核大,胞质少,细胞器少,癌细胞分化较差。结论:肝细胞癌的组织形态可以不同,诊断时应多切、多看、多比较,以其中主要的形态作为诊断的依据。
To investigate the relationship between the histological types and the degree of differentiation of hepatocellular carcinoma, paraffin sections of 60 cases were routinely prepared and 73 cases of hepatocellular carcinoma were ultrathin sectioned. The results showed that: ① The histological diversity of hepatocellular carcinoma, a slice can have two or more kinds of morphological changes. ② The morphology of HCC is relatively simple, the cancer cells are swollen, the nucleus is relatively small and the cell differentiation is relatively high. ③ cancer cells spindle or small cell shape, large nucleus, less cytoplasm, less organelles, poorly differentiated cancer cells. Conclusion: Histopathological changes of hepatocellular carcinoma may be different, diagnosis should be more than cut, see more and more, with the main form as the basis for diagnosis.