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目的：分析睾丸精原细胞瘤综合治疗的几个预后因素。方法：１９８４年～１９９６年间我院放疗科收治２１例睾丸精原细胞瘤，均行患侧睾丸副睾切除加精索高位结扎，术后均采用放疗或化疗。结果：２年生存率Ⅰ期患者为８３．３％（１０／１２）、Ⅱ期患者为１００％（７／７）、Ⅳ期患者为０（０／２）；５年生存率Ⅰ期患者为５８．３％（７／８）、Ⅱ期患者为８５．７％（６／７），Ⅳ期患者为０（０／１）。结论：Ⅰ期、Ⅱ期睾丸精原细胞瘤应行术后放疗，Ⅱ期应加用２～４周期化疗，综合治疗后可延长生存期。年龄对预后影响不明显，单纯化疗疗效有待进一步证实。
OBJECTIVE: To analyze several prognostic factors in the treatment of testicular seminoma. Methods: From 1984 to 1996, 21 cases of testicular seminoma were treated with radiotherapy or chemotherapy in our hospital. Results: The 2-year survival rate was 83.3% (10/12) in stage I patients, 100% (7/7) in stage II patients and 0 (0/2) in stage IV patients. The 5-year survival rate was significantly lower in stage I patients , 58.3% (7/8), 85.7% (6/7) in stage II and 0 (0/1) in stage IV. Conclusion: Stage Ⅰ and Ⅱ testicular seminoma should be treated with postoperative radiotherapy, and stage Ⅱ should be treated with 2 ~ 4 cycles of chemotherapy. After treatment, prolonged survival can be achieved. The effect of age on the prognosis is not obvious, the efficacy of chemotherapy alone needs to be further confirmed.