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背景胃食管反流病(gastroesophageal reflux disease,GERD)是胃、十二指肠内容物反流入食管引起症状和并发症,可伴有食管外表现。国外报道其与睡眠障碍有关。目的研究GERD患者中夜间烧心、反流症状的发生率,GERD对睡眠和一些日常活动的影响。方法通过对杭州市四大医院门诊的GERD患者以问卷调查的方式搜集资料,进行统计分析。结果调查的249名GERD患者中99名患者存在夜间烧心等引起的睡眠障碍,睡眠障碍好发于50岁以上患者(43.48%);睡眠障碍者多同时有日间及夜间烧心、反流症状(69.70%),绝大多数(97.98%)每周发生2次以上夜间烧心症状,并且46.47%睡眠障碍患者烧心症状受睡眠体位的影响;睡眠障碍多表现为睡眠维持障碍(82.83%)和睡眠质量下降(69.70%)。结论在GERD患者中,大部分患者均存在夜间烧心、反流等症状,从而导致夜间睡眠障碍,并且存在残留效应严重影响次日的学习和工作,应引起重视给予有效治疗。
Background Gastroesophageal reflux disease (GERD) is a gastroesophageal reflux reaction that causes the reflux of esophageal duodenal contents and causes complications and may be associated with extra-esophageal manifestations. Foreign reports of sleep disorders. Objective To study the incidence of nocturnal heartburn and reflux symptoms in GERD patients and the effect of GERD on sleep and some daily activities. Methods GERD patients from four major hospitals in Hangzhou were collected by means of questionnaire and analyzed statistically. Results Ninety-nine of 249 GERD patients were found to have nighttime heartburn caused by heartburn, sleep disorders occurred in patients over the age of 50 (43.48%); many sleep disorders both day and night heartburn, reflux symptoms ( 69.70%). Most of them (97.98%) experienced nighttime heartburn symptoms more than twice a week, and 46.47% of sleep disturbance patients were affected by sleep position. Sleep disorders manifested as sleep disturbance disorder (82.83%) and sleep quality Decline (69.70%). Conclusion In GERD patients, most patients have nighttime heartburn, reflux and other symptoms, resulting in night sleep disorders, and there are residual effects seriously affect the study and work the next day, should pay attention to give effective treatment.