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过去防治血栓形成,都是针对抑制血液的凝固性,但抗凝剂(如肝素)主要用于防止静脉血栓形成。对预防动脉血栓形成效果有限,因后者与血小板的关系比较密切。由于血管壁损伤引起血栓形成,以及刺激血管壁平滑肌细胞增殖使内膜增厚的机制中血小板都起到重要作用,促使学者们寻找用药物来影响血小板在这方面的作用,以达到预防及
In the past prevention and treatment of thrombosis, are aimed at inhibiting blood coagulation, but anticoagulants (such as heparin) is mainly used to prevent venous thrombosis. The prevention of arterial thrombosis is limited, because the latter is closely related to platelets. Platelets play an important role in thrombosis as a result of vascular wall injury and in the mechanism of intimal thickening stimulating the proliferation of vascular smooth muscle cells, prompting scholars to look for drugs that influence the effects of platelets in this regard, in order to achieve prevention and /