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邻苯二甲酸正丁酯在体外对多种白血病细胞具有抑制作用。在液体培养体系中,邻苯二甲酸正丁酯可选择性清除白血病祖细胞,而不影响正常造血细胞的生长,证明邻苯二甲酸正丁酯是一种有效可靠的体外净化剂,可用于临床白血病患者的骨髓体外净化。
N-Butylphthalate inhibits a variety of leukemic cells in vitro. In liquid culture systems, n-butyl phthalate selectively clears leukemic progenitor cells without affecting normal hematopoietic cell growth, demonstrating that n-butyl phthalate is an effective and reliable in vitro decontamination agent that can be used in In vitro purification of bone marrow in patients with clinical leukemia.