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目的:研究急性心肌梗死患者行直接冠状动脉介入治疗(PCI)的预后与超敏C反应蛋白(hs-CRP)水平的关系。方法:回顾我院2007年1月～2011年1月因急性心肌梗死行直接PCI的215例患者,比较了住院期间发生心血管事件组与未发生心血管事件组hs-CRP的水平,并根据hs-CRP水平将这些患者进行分组,比较不同水平hs-CRP组的心血管事件发生率。结果:急性心肌梗死行直接PCI患者住院期间发生心血管事件组hs-CRP的水平(10±4)mg/L与未发生心血管事件组hs-CRP的水平(6±5)mg/L具有显著差异(P<0.05)。hs-CRP 0～3 mg/L组、3～6 mg/L组、6～9 mg/L组、9～12 mg/L组和12～15 mg/L组心血管事件发生率分别为:23%、24%、47%、52%和70%。采用Logistic回归分析表明:用性别、年龄进行校正后,hs-CRP水平与心血管事件发生具有显著相关性(OR=1.188,P<0.01)。结论:hs-CRP可作为急性心肌梗死后行直接PCI患者预后的预测因子,hs-CRP水平越高,心血管事件发生率越高。
Objective: To investigate the relationship between the prognosis of patients undergoing direct coronary intervention (PCI) and the level of hs-CRP in patients with acute myocardial infarction. Methods: A retrospective review of 215 patients with PCI treated with acute myocardial infarction from January 2007 to January 2011 in our hospital was conducted. The levels of hs-CRP in patients with cardiovascular events and those without cardiovascular events during hospitalization were compared. Based on hs-CRP levels These patients were grouped to compare the incidence of cardiovascular events at different levels of hs-CRP. Results: The level of hs-CRP in the cardiovascular events group (10 ± 4) mg / L and the level of hs-CRP in the non-cardiovascular events group (6 ± 5) mg / L during PCI were significantly higher in patients with acute myocardial infarction Significant difference (P <0.05). The incidence of cardiovascular events in hs-CRP 0-3 mg / L, 3-6 mg / L, 6-9 mg / L, 9-12 mg / L and 12-15 mg / 23%, 24%, 47%, 52% and 70%. Logistic regression analysis showed that there was a significant correlation between hs-CRP levels and cardiovascular events after correction by sex and age (OR = 1.188, P <0.01). Conclusion: hs-CRP can be used as a predictor of prognosis in patients with direct PCI after acute myocardial infarction. The higher the hs-CRP level, the higher the incidence of cardiovascular events.