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四、其他氟的毒作用还很多,如对钙、磷代谢的影响(血清钙下降,磷升高)等已有许多报道,不予重复,需补充的有: 1.过量氟对酶活性的影响。酶是毒物作用的靶分子之一。国外已证明NaF具有抑制细胞生物物质合成酶的作用,F~-通过作用于某些酶的辅酶或激活物质,使酶的构型发生变化,从而影响到酶的活性。这
Fourth, there are many other toxic effects of fluorine, such as calcium and phosphorus metabolism (serum calcium decreased phosphorus increased) and so have been many reports, not repeat, need to add: 1. Excessive fluoride on enzyme activity influences. Enzymes are one of the target molecules for toxic effects. Abroad has proved that NaF inhibits the role of cell biosynthetic enzymes, F ~ - by acting on some enzymes coenzyme or activator, the enzyme configuration changes, thus affecting the enzyme activity. This