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近年来，在炎症过程中，尤其是哮喘，cAMP水平的变化普遍受到关注。细胞内cAMP水平的升高与多种细胞的功能抑制有关，其机制不完全清楚。cAMP的水平由受体耦联的腺苷酸环化酶（AC）依赖产生的cAMP的速率和3’5’磷酸二酯酶降解cAMP的速率决定。磷酸二酯酶（PDE）同功酶分为7个家
In recent years, changes in cAMP levels have been of general concern during the inflammatory process, especially asthma. Elevated intracellular cAMP level and a variety of cell function inhibition, the mechanism is not completely clear. The level of cAMP is determined by the rate of receptor-linked adenylyl cyclase (AC) -dependent cAMP production and the rate of cAMP degradation by 3 ’5’ phosphodiesterase. Phosphodiesterase (PDE) isozyme is divided into seven homes