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目的观察不同剂量胰岛素治疗糖尿病患者的临床效果。方法选择医院收治的100例2型糖尿病患者,按照随机数字表法分为观察组和对照组,每组50例。2组均给予胰岛素治疗,对照组给予门冬胰岛素30 0.5U·kg~(-1)·d~(-1),分2次于餐前30 min皮下注射,观察组给予门冬胰岛素30于餐前30 min皮下注射,每天3次。比较2组血糖相关指标。结果观察组空腹血糖、餐后2 h血糖、糖化血红蛋白低于对照组,空腹C肽、餐后C肽高于对照组,低血糖发生次数少于对照组,血糖达标时间短于对照组,差异均有统计学意义(P<0.05)。结论门冬胰岛素30于三餐前30 min皮下注射,能提高T2DM的治疗效果。
Objective To observe the clinical effect of different doses of insulin on diabetic patients. Methods A total of 100 patients with type 2 diabetes mellitus admitted to the hospital were randomly divided into observation group and control group according to the random number table method, with 50 cases in each group. Insulin treatment was given to both groups. The control group was given insulin aspart 30 0.5 U · kg ~ (-1) · d ~ (-1), subcutaneous injection 30 min before meals in 2 groups, and insulin aspart 30 Subcutaneous injection 30 min before meals, 3 times a day. Compare two groups of blood glucose related indicators. Results The fasting blood glucose, 2-hour postprandial blood glucose and glycosylated hemoglobin were lower in the observation group than those in the control group. The fasting C-peptide and postprandial C-peptide were higher in the observation group than in the control group. The incidence of hypoglycemia was less than that in the control group. All were statistically significant (P <0.05). Conclusion Aspart 30 could be injected subcutaneously 30 min before the three meals to improve the therapeutic effect of T2DM.