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目的:探讨观察扶正中药复方芪贞固本方联合DP方案治疗中晚期肺癌的疗效。方法:将符合纳入标准的60例患者随机分为扶正化疗组与单纯化疗组,均予DP方案化疗,但扶正化疗组在此基础上服用扶正中药复方,两个周期后,比较两组患者治疗前后瘤灶、主要症状、免疫功能变化及不良反应情况。结果:扶正化疗组相对单纯化疗组而言,可明显改善患者主要症状、提高患者生活质量、增强免疫功能、减轻不良反应,两组相比均有显著性差异(P<0.05),但两组在缩小和稳定病灶方面无显著性差异(P>0.05)。结论:扶正中药复方芪贞固本方联合DP方案治疗中晚期肺癌疗效肯定,具有增效减毒作用,值得深入研究。
Objective: To observe the therapeutic effect of Fuzheng Gubenfang combined with DP regimen in the treatment of advanced lung cancer. Methods: Sixty patients who met the inclusion criteria were randomly divided into two groups: Fuzheng chemotherapy group and chemotherapy group, all of which were given DP regimen chemotherapy. On the basis of Fuzheng chemotherapy group, Fuzheng herbal compound was taken. After two cycles, the two groups were compared Before and after the tumor, the main symptoms, changes in immune function and adverse reactions. Results: Compared with the chemotherapy alone group, Fuzheng chemotherapy group could significantly improve the main symptoms, improve the quality of life of patients, enhance the immune function and reduce the adverse reactions, there were significant differences between the two groups (P <0.05) There was no significant difference in reducing and stabilizing the lesions (P> 0.05). Conclusion: Fuzheng Chinese herbal compound Qizhen Guben prescription DP regimen in the treatment of advanced lung cancer efficacy is valid, with a synergistic effect of attenuated, it is worth further study.