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目的探讨无创机械通气治疗慢性阻塞性肺疾病(COPD)合并II型呼吸衰竭患者中的临床疗效。方法将90例患者随机分为对照组和观察组,各45例,对照组给予常规临床治疗,而观察组在常规治疗的基础上采用无创BiPAP呼吸机联合雾化吸入治疗;比较两组动脉血气指标、心率、呼吸、总有效率、生存质量等指标。结果治疗后,观察组的pH、PaCO2、PaO2、心率、呼吸等指标均明显好于对照组(P<0.01);观察组治疗后的总有效率为82.2%,明显高于对照组的51.1%(P<0.01);观察组治疗后的生存质量得分为96.20±8.93,好于对照组的105.59±7.46(P<0.01)。结论无创机械通气联合雾化吸入治疗COPD合并II型呼吸衰竭患者,可以明显改善心率、呼吸、动脉血气指标,提高总有效率和生存质量。
Objective To investigate the clinical efficacy of non-invasive mechanical ventilation in the treatment of patients with chronic obstructive pulmonary disease (COPD) and type II respiratory failure. Methods Ninety patients were randomly divided into control group and observation group, 45 cases in each group. The control group was given routine clinical treatment while the observation group was treated with noninvasive BiPAP ventilator combined with inhalation therapy on the basis of routine treatment. The arterial blood gas Indicators, heart rate, respiration, total effective rate, quality of life and other indicators. Results After treatment, the indexes such as pH, PaCO2, PaO2, heart rate and respiration in observation group were significantly better than those in control group (P <0.01). The total effective rate in observation group was 82.2%, significantly higher than that in control group (51.1% (P <0.01). The quality of life score of the observation group after treatment was 96.20 ± 8.93, which was better than that of the control group (105.59 ± 7.46, P <0.01). Conclusion Noninvasive mechanical ventilation combined with inhalation of inhalation in patients with COPD and type II respiratory failure can significantly improve heart rate, respiration and arterial blood gas indexes and improve the total effective rate and quality of life.