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目的:观察尼麦角林对短暂性脑缺血发作(TIA)患者脑血管反应性的影响。方法:选取TIA患者183例,随机分为对照组和试验组(尼麦角林组)。同时选择87例同期体检的健康人作为健康对照组。治疗前和治疗2周后对三组分别采用TCD屏气试验检测屏气指数(BHI)作为CVR的评价指标。结果:治疗前对照组和试验组的BHI较健康对照组降低;治疗后对照组和试验组的BHI比治疗前提高,且实验组升高明显。结论:尼麦角林可提高TIA患者的脑血管反应性,改善患者预后。
Objective: To observe the effect of nicergoline on cerebrovascular reactivity in patients with transient ischemic attack (TIA). Methods: 183 TIA patients were selected and randomly divided into control group and experimental group (nicergoline group). At the same time select 87 cases of healthy people as the healthy control group. Before treatment and after 2 weeks of treatment, breath holding index (BHI) was measured by TCD breath test in each group as the evaluation index of CVR. Results: Before treatment, the BHI in the control group and the experimental group was lower than that in the healthy control group. After treatment, the BHI in the control group and the experimental group was higher than that before treatment, and the experimental group increased significantly. Conclusion: Nicergoline can improve cerebrovascular reactivity in patients with TIA and improve the prognosis of patients.