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目的:提高对前列腺副神经节瘤的认识和诊治水平。方法:报告确诊前列腺副神经节瘤1例,肿瘤组织行神经元特异性烯醇化酶(NSE)、嗜铬A、突触素(Syn)、S-100和前列腺特异性抗原(PSA)免疫组化染色。结合文献复习,总结其临床、病理和治疗情况。结果:这1例前列腺副神经节瘤以血精就诊。行前列腺根治切除术,病理检查符合副神经节瘤组织学特征,免疫组化染色:NSE、嗜铬A、Syn、S-100阳性,PSA阴性。随访42个月,排尿和排便通畅,疗效满意,无转移和复发。结论:前列腺是肾上腺外副神经节瘤极少见的位置,临床非常罕见。前列腺副神经节瘤的临床和病理特征具有特殊性,需病理确诊,治疗宜手术完整切除肿瘤,术后应密切随访。
Objective: To improve the understanding and diagnosis and treatment of paraganglioma of the prostate. Methods: One case of paraganglioma of the prostate was diagnosed. NSE, Syn, S-100 and PSA immunohistochemistry were performed in the tumor tissue. Staining. Combined with the literature review, summarizes its clinical, pathological and therapeutic situation. Results: This one case of paraganglioma was treated with blood serum. Radical radical prostatectomy, pathological examination in line with the paraganglioma histological features, immunohistochemical staining: NSE, Chromium A, Syn, S-100 positive, PSA negative. Follow-up 42 months, voiding and defecation unobstructed, with satisfactory results, no transfer and recurrence. Conclusion: The prostate is a rare site of adrenal paraganglioma, which is rare in clinic. Prostate paraganglioma clinical and pathological features of a particular, need pathological diagnosis, treatment should be complete removal of the tumor surgery, should be followed up after surgery.